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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 67382
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Klkb1
Name: kallikrein B1
Acc ID: CHEBI:28158
Term: 6-oxoprostaglandin F1alpha
Definition: A prostaglandin Falpha that is prostaglandin F1alpha bearing a keto substituent at the 6-position.
Chemical ID: MESH:D015121
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Klkb1increases abundanceISORGD:108436480464CTDKLKB1 gene mutant form results in increased abundance of 6-Ketoprostaglandin F1 alphaPMID:25339356
Klkb1multiple interactionsISORGD:108436480464CTD7-Ala-angiotensin (1-7) inhibits the reaction [KLKB1 gene mutant form results in increased abundance of 6-Ketoprostaglandin F1 alpha]; nimesulide inhibits the reaction [KLKB1 gene mutant form results in increased abundance of 6-Ketoprostaglandin F1 alpha]PMID:25339356
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