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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736306
Species: Homo sapiens
RGD Object: Gene
Symbol: IL4
Name: interleukin 4
Acc ID: CHEBI:28148
Term: sodium stibogluconate
Definition: A D-gluconate adduct of indefinite composition containing between 30 and 34% of antimony(V), calculated with reference to dried and methanol-free substance. It is used as a treatment for leishmaniasis.
Chemical ID: MESH:D000967
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL4decreases expressionEXP 6480464CTDAntimony Sodium Gluconate results in decreased expression of IL4 mRNAPMID:20102417
IL4affects response to substanceISOIl4 (Mus musculus)6480464CTDIL4 protein affects the susceptibility to Antimony Sodium GluconatePMID:11069076 PMID:7960131
IL4multiple interactionsISOIl4 (Mus musculus)6480464CTD[IFNG protein co-treated with Antimony Sodium Gluconate] results in decreased expression of IL4 mRNAPMID:9234779
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