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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620942
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dnaja1
Name: DnaJ heat shock protein family (Hsp40) member A1
Acc ID: CHEBI:2814
Term: arecoline
Definition: A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.
Chemical ID: MESH:D001115
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:7344136480464CTDArecoline results in increased expression of DNAJA1 mRNA

PMID:17682004
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.