Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	735779
Species:	Homo sapiens
RGD Object:	Gene
Symbol:	DIO2
Name:	iodothyronine deiodinase 2

Acc ID:	CHEBI:28121
Term:	harmine
Definition:	A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7.
Chemical ID:	MESH:D006247

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
DIO2	increases expression	ISO	Dio2 (Mus musculus)	6480464	CTD	Harmine results in increased expression of DIO2 protein	PMID:27805061

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.