GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Dyrk1a | decreases expression | ISO | Dyrk1a (Rattus norvegicus) | 11097969 | RGD | harmine decreases expression of dyrk1a protein after myocardial infarction in rat heart left ventricle | | Dyrk1a | affects binding | ISO | DYRK1A (Homo sapiens) | 6480464 | CTD | Harmine binds to DYRK1A protein | PMID:25751815 | Dyrk1a | decreases activity | ISO | DYRK1A (Homo sapiens) | 6480464 | CTD | Harmine results in decreased activity of DYRK1A protein | PMID:21573099 | Dyrk1a | multiple interactions | ISO | DYRK1A (Homo sapiens) | 6480464 | CTD | Harmine inhibits the reaction [DYRK1A protein results in increased phosphorylation of MAPT protein] | PMID:21573099 | |
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