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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737342
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp24a1
Name: cytochrome P450, family 24, subfamily a, polypeptide 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp24a1decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of CYP24A1 mRNAPMID:29673856
Cyp24a1multiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CYP24A1 mRNAPMID:17942748
Cyp24a1increases expressionISOCYP24A1 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of CYP24A1 mRNAPMID:20106945 PMID:21632981 PMID:26238291
Cyp24a1increases expressionISOCyp24a1 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of CYP24A1 mRNAPMID:33387578
Cyp24a1multiple interactionsISOCYP24A1 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]PMID:19244278
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