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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736861
Species: Homo sapiens
RGD Object: Gene
Symbol: RAP2B
Name: RAP2B, member of RAS oncogene family
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RAP2Bincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of RAP2B mRNAPMID:21632981
RAP2Baffects expressionISORap2b (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of RAP2B mRNAPMID:21570461
RAP2Bdecreases expressionISORap2b (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of RAP2B mRNAPMID:33387578
RAP2Bincreases expressionISORap2b (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of RAP2B mRNAPMID:19770486
RAP2Bmultiple interactionsISORap2b (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with AHR gene mutant form] results in decreased expression of RAP2B mRNA; [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RAP2B mRNAPMID:17942748 PMID:19465110
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