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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736466
Species: Homo sapiens
RGD Object: Gene
Symbol: OGT
Name: O-linked N-acetylglucosamine (GlcNAc) transferase
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
OGTaffects expressionISOOgt (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of OGT mRNAPMID:22298810
OGTaffects expressionISOOgt (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of OGT mRNAPMID:21570461
OGTdecreases expressionISOOgt (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of OGT mRNAPMID:21215274 PMID:33387578
OGTmultiple interactionsISOOgt (Mus musculus)6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to OGT promoter]PMID:19654925
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