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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735763
Species: Mus musculus
RGD Object: Gene
Symbol: Hey1
Name: hairy/enhancer-of-split related with YRPW motif 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hey1affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of HEY1 mRNAPMID:21570461 PMID:24058054
Hey1increases expressionISOHey1 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of HEY1 mRNAPMID:32109520 PMID:33387578
Hey1increases expressionISOHEY1 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of HEY1 mRNAPMID:19619570 PMID:20106945 PMID:21632981 PMID:26238291
Hey1multiple interactionsISOHEY1 (Homo sapiens)6480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of HEY1 mRNAPMID:19619570
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