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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735018
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bpgm
Name: bisphosphoglycerate mutase
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bpgmdecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of BPGM mRNAPMID:21215274 PMID:33387578
Bpgmmultiple interactionsEXP 6480464CTDAHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of BPGM mRNA]PMID:21215274
Bpgmdecreases expressionISOBPGM (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of BPGM mRNAPMID:23152189
Bpgmincreases expressionISOBpgm (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of BPGM mRNAPMID:19933214
Bpgmmultiple interactionsISOBPGM (Homo sapiens)6480464CTD2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of BPGM mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of BPGM mRNA]PMID:23152189
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