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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734439
Species: Homo sapiens
RGD Object: Gene
Symbol: UPB1
Name: beta-ureidopropionase 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
UPB1decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of UPB1 mRNAPMID:20106945 PMID:21998131
UPB1increases expressionISOUpb1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of UPB1 mRNAPMID:18796159 PMID:19770486 PMID:20819909
UPB1multiple interactionsISOUpb1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to UPB1 gene]PMID:20819909
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