GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | GPT | affects expression | ISO | Gpt (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of GPT mRNA | PMID:21570461 | GPT | decreases expression | ISO | Gpt (Rattus norvegicus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of GPT mRNA | PMID:16054898 PMID:16960034 PMID:21215274 PMID:33387578 | GPT | decreases expression | ISO | Gpt (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of GPT mRNA; Tetrachlorodibenzodioxin results in decreased expression of GPT protein | PMID:15722456 PMID:16960034 | GPT | increases activity | ISO | Gpt (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased activity of GPT protein | PMID:26862745 | GPT | multiple interactions | ISO | Gpt (Mus musculus) | 6480464 | CTD | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GPT mRNA; AHRR protein affects the reaction [Tetrachlorodibenzodioxin results in increased activity of GPT protein] | PMID:17942748 PMID:26862745 | |
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