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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733946
Species: Homo sapiens
RGD Object: Gene
Symbol: CRNKL1
Name: crooked neck pre-mRNA splicing factor 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CRNKL1affects expressionISOCrnkl1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of CRNKL1 mRNAPMID:21570461
CRNKL1increases expressionISOCrnkl1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of CRNKL1 mRNAPMID:17942748
CRNKL1multiple interactionsISOCrnkl1 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CRNKL1 mRNAPMID:17942748
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