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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733821
Species: Homo sapiens
RGD Object: Gene
Symbol: GRIA4
Name: glutamate ionotropic receptor AMPA type subunit 4
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GRIA4decreases expressionISOGria4 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of GRIA4 mRNAPMID:32109520
GRIA4increases expressionISOGria4 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of GRIA4 mRNAPMID:21354282
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