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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733759
Species: Homo sapiens
RGD Object: Gene
Symbol: ACADL
Name: acyl-CoA dehydrogenase long chain
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACADLdecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of ACADL mRNAPMID:20106945
ACADLincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of ACADL mRNAPMID:21296121
ACADLaffects expressionISOAcadl (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of ACADL mRNAPMID:34747641
ACADLdecreases expressionISOAcadl (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of ACADL mRNAPMID:11752688
ACADLmultiple interactionsISOAcadl (Mus musculus)6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ACADL promoter]PMID:19654925
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