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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733136
Species: Homo sapiens
RGD Object: Gene
Symbol: ANGPT1
Name: angiopoietin 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ANGPT1affects expressionISOAngpt1 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of ANGPT1 mRNAPMID:32109520
ANGPT1decreases expressionISOAngpt1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of ANGPT1 mRNAPMID:16120747
ANGPT1increases expressionISOAngpt1 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of ANGPT1 mRNAPMID:24475139
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