GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Jup | affects expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of JUP mRNA | PMID:21570461 | Jup | decreases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of JUP mRNA | PMID:23690540 | Jup | increases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of JUP mRNA | PMID:17035482 PMID:17586704 | Jup | multiple interactions | EXP | | 6480464 | CTD | [Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in decreased expression of JUP mRNA; [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of JUP mRNA | PMID:23690540 PMID:25975270 | Jup | decreases expression | ISO | Jup (Rattus norvegicus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of JUP mRNA | PMID:12478657 PMID:23690540 | Jup | increases expression | ISO | Jup (Rattus norvegicus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of JUP mRNA | PMID:34747641 | Jup | increases expression | ISO | JUP (Homo sapiens) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of JUP mRNA; Tetrachlorodibenzodioxin results in increased expression of JUP protein | PMID:20106945 PMID:21632981 PMID:23152189 PMID:37788135 | Jup | multiple interactions | ISO | Jup (Rattus norvegicus) | 6480464 | CTD | [Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in decreased expression of JUP mRNA; Tetrachlorodibenzodioxin affects the localization of and results in decreased expression of JUP protein; Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to JUP promoter] | PMID:12478657 PMID:23690540 | |
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