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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732246
Species: Homo sapiens
RGD Object: Gene
Symbol: CNR2
Name: cannabinoid receptor 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CNR2multiple interactionsEXP 6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CNR2 gene]PMID:28681081
CNR2affects expressionISOCnr2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of CNR2 mRNAPMID:22298810
CNR2decreases expressionISOCnr2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of CNR2 mRNAPMID:21215274
CNR2multiple interactionsISOCnr2 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CNR2 mRNAPMID:17942748
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