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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732179
Species: Homo sapiens
RGD Object: Gene
Symbol: POLG
Name: DNA polymerase gamma, catalytic subunit
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
POLGmultiple interactionsEXP 6480464CTD[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of POLG mRNAPMID:14761676
POLGaffects expressionISOPolg (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of POLG mRNAPMID:21570461
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