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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731690
Species: Homo sapiens
RGD Object: Gene
Symbol: PLEC
Name: plectin
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PLECincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of PLEC mRNAPMID:22903824
PLECaffects expressionISOPlec (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of PLEC mRNAPMID:34747641
PLECaffects expressionISOPlec (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of PLEC mRNAPMID:21570461
PLECdecreases expressionISOPlec (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PLEC mRNA; Tetrachlorodibenzodioxin results in decreased expression of PLEC proteinPMID:16548065 PMID:21215274 PMID:32109520 PMID:33387578
PLECincreases expressionISOPlec (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of PLEC mRNAPMID:17035482
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