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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70974
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kif2a
Name: kinesin family member 2A
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kif2adecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of KIF2A mRNAPMID:33387578 PMID:34747641
Kif2aaffects expressionISOKif2a (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of KIF2A mRNAPMID:21570461
Kif2adecreases expressionISOKif2a (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of KIF2A mRNAPMID:19770486
Kif2amultiple interactionsISOKif2a (Mus musculus)6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to KIF2A promoter]PMID:19654925
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