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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70372
Species: Homo sapiens
RGD Object: Gene
Symbol: ACOT8
Name: acyl-CoA thioesterase 8
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACOT8affects expressionISOAcot8 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of ACOT8 mRNAPMID:20702594 PMID:21570461
ACOT8increases expressionISOAcot8 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of ACOT8 mRNAPMID:17942748
ACOT8increases expressionISOAcot8 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of ACOT8 mRNAPMID:33387578
ACOT8multiple interactionsISOAcot8 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of ACOT8 mRNAPMID:28433925
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