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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631427
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cryl1
Name: crystallin, lambda 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cryl1decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of CRYL1 mRNAPMID:21215274
Cryl1increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of CRYL1 mRNAPMID:20558275 PMID:32109520 PMID:33387578
Cryl1affects expressionISOCryl1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of CRYL1 mRNAPMID:21570461
Cryl1increases expressionISOCRYL1 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of CRYL1 mRNAPMID:19684285 PMID:20106945 PMID:21632981
Cryl1multiple interactionsISOCRYL1 (Homo sapiens)6480464CTD[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CRYL1 mRNAPMID:19684285
Cryl1multiple interactionsISOCryl1 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CRYL1 mRNAPMID:17942748
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