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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628812
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pdp2
Name: pyruvate dehydrogenase phosphatase catalytic subunit 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdp2decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of PDP2 mRNAPMID:20959002 PMID:21215274 PMID:33387578
Pdp2increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of PDP2 mRNAPMID:32109520
Pdp2decreases expressionISOPDP2 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PDP2 mRNAPMID:20106945 PMID:21632981
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