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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62225
Species: Mus musculus
RGD Object: Gene
Symbol: Fah
Name: fumarylacetoacetate hydrolase
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fahaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of FAH mRNAPMID:21570461
Fahdecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of FAH mRNAPMID:19770486
Fahmultiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FAH mRNAPMID:17942748
Fahdecreases expressionISOFah (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of FAH mRNAPMID:21215274 PMID:21724226
Fahincreases expressionISOFah (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of FAH mRNAPMID:33387578
Fahincreases expressionISOFAH (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of FAH mRNAPMID:20106945 PMID:21632981
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