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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621817
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pola2
Name: DNA polymerase alpha 2, accessory subunit
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pola2decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of POLA2 mRNAPMID:34747641
Pola2increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of POLA2 mRNAPMID:16960034
Pola2affects expressionISOPola2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of POLA2 mRNAPMID:21570461
Pola2increases expressionISOPola2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of POLA2 mRNAPMID:16960034 PMID:19465110
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