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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621636
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pex3
Name: peroxisomal biogenesis factor 3
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pex3decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of PEX3 mRNAPMID:34747641
Pex3increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of PEX3 mRNAPMID:33387578
Pex3affects expressionISOPEX3 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin affects the expression of PEX3 mRNAPMID:22574217
Pex3affects expressionISOPex3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of PEX3 mRNAPMID:21570461
Pex3increases expressionISOPex3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of PEX3 mRNAPMID:19465110
Pex3multiple interactionsISOPex3 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PEX3 mRNAPMID:17942748
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