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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621261
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pla1a
Name: phospholipase A1 member A
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pla1aaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of PLA1A mRNAPMID:34747641
Pla1adecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of PLA1A mRNAPMID:21215274 PMID:32109520
Pla1aaffects expressionISOPla1a (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of PLA1A mRNAPMID:21570461 PMID:26377647
Pla1aaffects expressionISOPLA1A (Homo sapiens)6480464CTDTetrachlorodibenzodioxin affects the expression of PLA1A mRNAPMID:22298810
Pla1adecreases expressionISOPla1a (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PLA1A mRNAPMID:26290441
Pla1amultiple interactionsISOPla1a (Mus musculus)6480464CTD[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of PLA1A mRNAPMID:25975270
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