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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62097
Species: Mus musculus
RGD Object: Gene
Symbol: Fgf7
Name: fibroblast growth factor 7
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fgf7increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of FGF7 mRNAPMID:15034205
Fgf7multiple interactionsEXP 6480464CTDTetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of FGF7 mRNA]PMID:16054899
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