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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62086
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Acsm3
Name: acyl-CoA synthetase medium-chain family member 3
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acsm3decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of ACSM3 mRNA; Tetrachlorodibenzodioxin results in decreased expression of SAH mRNAPMID:18796159 PMID:21215274 PMID:21724226
Acsm3affects expressionISOAcsm3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of ACSM3 mRNAPMID:26377647
Acsm3decreases expressionISOAcsm3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of ACSM3 mRNAPMID:19770486 PMID:22539624
Acsm3decreases expressionISOACSM3 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of ACSM3 mRNAPMID:21998131
Acsm3multiple interactionsISOAcsm3 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of ACSM3 mRNAPMID:28433925
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