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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620696
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Chd8
Name: chromodomain helicase DNA binding protein 8
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chd8decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of CHD8 mRNAPMID:33387578
Chd8increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of CHD8 mRNAPMID:34747641
Chd8affects expressionISOChd8 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of CHD8 mRNAPMID:21570461 PMID:24680724
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