Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620601
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ackr3
Name: atypical chemokine receptor 3
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ackr3affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of ACKR3 mRNAPMID:22298810
Ackr3decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of ACKR3 mRNAPMID:33387578
Ackr3increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of ACKR3 mRNAPMID:16054898 PMID:18796159 PMID:21215274 PMID:27136898 PMID:32109520
Ackr3affects expressionISOAckr3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of ACKR3 mRNAPMID:21570461 PMID:26377647
Ackr3decreases expressionISOACKR3 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of ACKR3 mRNAPMID:19619570
Ackr3decreases expressionISOAckr3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of ACKR3 mRNAPMID:18691609 PMID:19933214
Ackr3increases expressionISOAckr3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of ACKR3 mRNAPMID:18796159 PMID:26290441
Ackr3multiple interactionsISOACKR3 (Homo sapiens)6480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of ACKR3 mRNAPMID:19619570
Ackr3multiple interactionsISOAckr3 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of ACKR3 mRNAPMID:16214954
Go Back to source page   Continue to Ontology report