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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620462
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pim3
Name: Pim-3 proto-oncogene, serine/threonine kinase
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pim3affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of PIM3 mRNAPMID:22298810
Pim3decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of PIM3 mRNAPMID:21215274
Pim3increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of PIM3 mRNAPMID:33387578 PMID:34747641
Pim3affects expressionISOPim3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of PIM3 mRNAPMID:21570461
Pim3decreases expressionISOPIM3 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PIM3 mRNAPMID:20106945 PMID:21632981
Pim3multiple interactionsISOPim3 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PIM3 mRNAPMID:17942748
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