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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3086
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kitlg
Name: KIT ligand
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kitlgaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of KITLG mRNAPMID:22298810 PMID:34747641
Kitlgdecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of KITLG mRNAPMID:33387578
Kitlgmultiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in decreased expression of KITL mRNAPMID:21602191
Kitlgaffects expressionISOKitl (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of KITL mRNAPMID:18691609 PMID:21570461
Kitlgdecreases expressionISOKitl (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of KITL mRNAPMID:19770486
Kitlgincreases expressionISOKITLG (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of KITLG mRNAPMID:21296121
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