A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID:
MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Dexamethasone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Dicumarol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]]
Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA; Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA alternative form
2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; [Acetylcysteine co-treated with chromium trioxide] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of NQO1 mRNA; [Tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with Dietary Fats] results in decreased expression of NQO1 mRNA; [Tetrachlorodibenzodioxin co-treated with chromium trioxide co-treated with Buthionine Sulfoximine] results in increased expression of NQO1 mRNA; [Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in increased expression of NQO1 mRNA; [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of NQO1 mRNA; Acetylcysteine inhibits the reaction [Cadmium Chloride promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]]; Acetylcysteine inhibits the reaction [sodium arsenite promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]]; AG-879 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 protein]; ammonium metavanadate affects the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; ammonium metavanadate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 protein]; Arsenic promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Arsenic Trioxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; arsenite affects the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; arsenite promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]]; Buthionine Sulfoximine inhibits the reaction [chromium trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]]; Buthionine Sulfoximine inhibits the reaction [sodium arsenite promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]]; Buthionine Sulfoximine promotes the reaction [Arsenic Trioxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]]; Buthionine Sulfoximine promotes the reaction [Cadmium Chloride promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]]; Cadmium Chloride promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; Cadmium Chloride promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Cadmium promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; Cadmium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Chromium inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; Chromium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Chromium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; chromium trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; CHUK protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Copper inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; Copper inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Dactinomycin promotes the reaction [Chromium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]]; Demecolcine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Lead promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; Lead promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 protein]; NFE2L2 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 protein]; PLA2G4A protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; sodium arsenite promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; sodium arsenite promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of NQO1 protein]; sodium arsenite promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [NFE2L2 gene mutant form results in decreased expression of NQO1 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of NQO1 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to NQO1 promoter]; Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of NQO1 protein; TIPARP gene mutant form promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; trimethylarsine oxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of NQO1 protein]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; [Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]] which results in decreased expression of NQO1 mRNA; [Tetrachlorodibenzodioxin co-treated with Mitomycin co-treated with Oxygen deficiency] affects the activity of NQO1 protein; [Tetrachlorodibenzodioxin co-treated with Mitomycin] results in decreased activity of NQO1 protein; [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] which results in increased expression of NQO1 mRNA; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 protein]; AHR mutant form inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]]; ammonium metavanadate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of NQO1 protein]; ammonium metavanadate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Cacodylic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of NQO1 protein]; Cacodylic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; CYP1A1 protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Mercuric Chloride promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of NQO1 protein]; Mercuric Chloride promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; monomethylarsonic acid promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; monomethylarsonic acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 protein]; Tetrachlorodibenzodioxin promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]; Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of NQO1 protein; TGFB1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; trimethylarsine oxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of NQO1 protein]; trimethylarsine oxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]
