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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2422
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Crygd
Name: crystallin, gamma D
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Crygddecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of CRYGD mRNAPMID:20959002
Crygdmultiple interactionsISOCrygd (Mus musculus)6480464CTDCRYGD promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]PMID:23997114
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