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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2371
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Col10a1
Name: collagen type X alpha 1 chain
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Col10a1affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of COL10A1 mRNAPMID:32109520
Col10a1multiple interactionsISOCol10a1 (Mus musculus)6480464CTD[AHR gene mutant form results in decreased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of COL10A1 mRNAPMID:24035824
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