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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2237
Species: Rattus norvegicus
RGD Object: Gene
Symbol: C5
Name: complement C5
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
C5affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of C5 mRNAPMID:22298810
C5increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of C5 mRNAPMID:32109520
C5affects expressionISOHc (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of HC mRNAPMID:26377647
C5decreases expressionISOC5 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of C5 mRNAPMID:15056799 PMID:20106945
C5increases expressionISOC5 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of C5 mRNAPMID:11489354
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