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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2155
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Arpc1b
Name: actin related protein 2/3 complex, subunit 1B
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Arpc1baffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of ARPC1B mRNAPMID:34747641
Arpc1bincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of ARPC1B mRNAPMID:33387578
Arpc1baffects expressionISOArpc1b (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of ARPC1B mRNAPMID:21570461
Arpc1bincreases expressionISOARPC1B (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of ARPC1B mRNAPMID:20106945 PMID:21632981
Arpc1bmultiple interactionsISOArpc1b (Mus musculus)6480464CTD[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of ARPC1B mRNAPMID:25975270
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