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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1620858
Species: Mus musculus
RGD Object: Gene
Symbol: Ptges3
Name: prostaglandin E synthase 3
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptges3affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of PTGES3 mRNAPMID:21570461
Ptges3decreases expressionISOPtges3 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PTGES3 mRNAPMID:34747641
Ptges3increases expressionISOPTGES3 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of PTGES3 mRNAPMID:21998131
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