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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1616667
Species: Mus musculus
RGD Object: Gene
Symbol: Nucks1
Name: nuclear casein kinase and cyclin-dependent kinase substrate 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nucks1affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of NUCKS1 mRNAPMID:21570461
Nucks1multiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with AHR gene mutant form] results in decreased expression of NUCKS1 mRNAPMID:19465110
Nucks1affects expressionISONucks1 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of NUCKS1 mRNAPMID:34747641
Nucks1decreases expressionISONucks1 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of NUCKS1 mRNAPMID:33387578
Nucks1increases expressionISONUCKS1 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of NUCKS1 mRNAPMID:19684285
Nucks1multiple interactionsISONUCKS1 (Homo sapiens)6480464CTD[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of NUCKS1 mRNAPMID:19684285
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