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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1605852
Species: Homo sapiens
RGD Object: Gene
Symbol: TMTC2
Name: transmembrane O-mannosyltransferase targeting cadherins 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TMTC2increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of TMTC2 mRNAPMID:22903824
TMTC2affects expressionISOTmtc2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of TMTC2 mRNAPMID:21570461
TMTC2increases expressionISOTmtc2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of TMTC2 mRNAPMID:28922406
TMTC2multiple interactionsISOTmtc2 (Mus musculus)6480464CTD[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of TMTC2 mRNAPMID:25975270
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