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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1604395
Species: Homo sapiens
RGD Object: Gene
Symbol: SORBS3
Name: sorbin and SH3 domain containing 3
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SORBS3affects expressionISOSorbs3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of SORBS3 mRNAPMID:21570461
SORBS3affects expressionISOSorbs3 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of SORBS3 mRNAPMID:22298810
SORBS3decreases expressionISOSorbs3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of SORBS3 mRNAPMID:19770486 PMID:19933214
SORBS3decreases expressionISOSorbs3 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of SORBS3 mRNAPMID:21215274
SORBS3increases expressionISOSorbs3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of SORBS3 mRNAPMID:17942748
SORBS3increases expressionISOSorbs3 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of SORBS3 mRNAPMID:33387578
SORBS3multiple interactionsISOSorbs3 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SORBS3 mRNAPMID:17942748
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