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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1602959
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC35E4
Name: solute carrier family 35 member E4
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC35E4multiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] results in decreased expression of SLC35E4 mRNAPMID:29704546
SLC35E4affects expressionISOSlc35e4 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of SLC35E4 mRNAPMID:21570461
SLC35E4decreases expressionISOSlc35e4 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of SLC35E4 mRNAPMID:34747641
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