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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1592688
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rusc2
Name: RUN and SH3 domain containing 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rusc2affects expressionISORusc2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of RUSC2 mRNAPMID:21570461
Rusc2increases expressionISORusc2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of RUSC2 mRNAPMID:19933214
Rusc2multiple interactionsISORusc2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to RUSC2 promoter]PMID:19654925
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