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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1589953
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc25a45
Name: solute carrier family 25, member 45
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc25a45increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of SLC25A45 mRNAPMID:32109520
Slc25a45affects expressionISOSlc25a45 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of SLC25A45 mRNAPMID:21570461
Slc25a45affects expressionISOSLC25A45 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin affects the expression of SLC25A45 mRNAPMID:22574217
Slc25a45multiple interactionsISOSlc25a45 (Mus musculus)6480464CTD[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of SLC25A45 mRNAPMID:25975270
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