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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1589750
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hao1
Name: hydroxyacid oxidase 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hao1affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of HAO1 mRNAPMID:22298810
Hao1decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of HAO1 mRNAPMID:21215274 PMID:21724226
Hao1affects expressionISOHao1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of HAO1 mRNAPMID:21570461 PMID:26377647
Hao1decreases expressionISOHao1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of HAO1 mRNA; Tetrachlorodibenzodioxin results in decreased expression of HAO1 proteinPMID:19770486 PMID:26290441 PMID:27562557 PMID:28213091 PMID:28922406
Hao1multiple interactionsISOHao1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to HAO1 gene]PMID:28213091
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