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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1589685
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Arl4c
Name: ADP ribosylation factor like GTPase 4C
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Arl4caffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of ARL4C mRNAPMID:22298810
Arl4caffects expressionISOArl4c (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of ARL4C mRNAPMID:21570461
Arl4cdecreases expressionISOArl4c (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of ARL4C mRNAPMID:19770486
Arl4cincreases expressionISOARL4C (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of ARL4C mRNAPMID:27913140
Arl4cmultiple interactionsISOArl4c (Mus musculus)6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ARL4C promoter]PMID:19654925
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