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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1558477
Species: Mus musculus
RGD Object: Gene
Symbol: Trpm2
Name: transient receptor potential cation channel, subfamily M, member 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpm2affects expressionISOTrpm2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of TRPM2 mRNAPMID:22298810
Trpm2decreases expressionISOTrpm2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of TRPM2 mRNAPMID:21724226
Trpm2increases expressionISOTrpm2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of TRPM2 mRNAPMID:33387578
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