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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1557505
Species: Mus musculus
RGD Object: Gene
Symbol: Atoh8
Name: atonal bHLH transcription factor 8
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atoh8affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of ATOH8 mRNAPMID:21570461 PMID:26377647
Atoh8decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of ATOH8 proteinPMID:25703434
Atoh8increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of ATOH8 mRNAPMID:16214954 PMID:21889950 PMID:25703434 PMID:25975270 PMID:26290441
Atoh8multiple interactionsEXP 6480464CTD[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of ATOH8 mRNAPMID:25975270
Atoh8increases expressionISOATOH8 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of ATOH8 mRNAPMID:20106945 PMID:21632981
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